FRIDAY, Sept. four, 2020 (HealthDay News)
Individuals with lupus usually are not at enhanced risk of hospitalization from COVID-19 because of to steroidal medicines they acquire to minimize immune method activity, a new study finds.
And a associated study uncovered that persons with inflammatory kinds of arthritis — these types of as rheumatoid arthritis — usually are not much more most likely to be hospitalized with COVID-19 than persons without having arthritis.
Both equally experiments were led by scientists at NYU Grossman Faculty of Medication, in New York City.
The findings “need to reassure most people, particularly those people on immunosuppressant therapy, that they are at no increased risk of getting to be admitted to clinic from COVID-19 than other lupus or arthritis people,” Dr. Ruth Fernandez-Ruiz, co-creator of the experiments, claimed in an NYU Langone news release.
“Individuals with lupus or inflammatory arthritis have the identical risk components for finding severely unwell from COVID-19 as persons without having these conditions,” claimed Fernandez-Ruiz, a postdoctoral fellow in rheumatology.
Lupus and disorders like rheumatoid arthritis, psoriatic arthritis and spondyloarthritis are autoimmune diseases in which the immune method mistakenly assaults a person’s own tissues. This leads to irritation in the joints, pores and skin, kidneys and other components of the overall body.
The scientists uncovered that lupus people taking immune-suppressing medicines — these types of as mycophenolate mofetil (CellCept) and azathioprine (Imuran) — had no increased risk of hospitalization (15 out of 24) than lupus people not using the medicines (9 of seventeen).
In addition, the COVID-19 hospitalization fee for persons with inflammatory arthritis (26%) was comparable to that of New York City people over-all (25%).
Another discovering was that people taking biologic drugs for arthritis, these types of as adalimumab (Humira) and etanercept (Enbrel), or the antiviral hydroxychloroquine, had no increased or reduced risk of COVID-19 hospitalization than those people not taking the drugs.
But people who took steroids identified as glucocorticoids, even in gentle doses, had a ten moments increased risk of COVID-19 hospitalization than those people who failed to acquire steroids. While the discovering is statistically considerable, the study’s little size may perhaps overestimate the actual risk, the scientists famous.
The experiments were not long ago revealed on the net in the journal Arthritis and Rheumatology.
— Robert Preidt
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Resource: NYU Langone, news release, Aug. 25, 2020