L-arginine – Mayo Clinic

Overview

L-arginine is an amino acid that can help the body construct protein.

Your body commonly tends to make all the L-arginine it desires. L-arginine is also identified in most protein-prosperous food items, such as fish, purple meat, poultry, soy, entire grains, beans and dairy items.

As a dietary supplement, L-arginine can be utilised orally and topically. It can also be administered intravenously (IV).

Mainly because L-arginine acts as a vasodilator, opening (dilating) blood vessels, numerous people today choose oral L-arginine to address coronary heart ailments and erectile dysfunction.

Proof

Investigation on the use of L-arginine for certain ailments shows:

  • Angina. Research suggest that L-arginine could decrease indications and enhance excellent of lifetime in people today with a gentle to intense form of this kind of upper body pain.
  • Superior blood pressure (hypertension). Some exploration has shown that oral L-arginine can decrease blood pressure in nutritious people today, people today with gentle blood pressure elevation and diabetic issues, and in people today with a kind of significant blood pressure that influences the arteries in the lungs and the right facet of the coronary heart (pulmonary hypertension). Infusions of L-arginine also appear to decrease blood pressure in people today with hypertension.
  • Superior blood pressure in the course of being pregnant. Some research demonstrate that L-arginine infusions may well decrease blood pressure in expecting gals who build significant blood pressure.
  • Preeclampsia. L-arginine infusions may well decrease blood pressure in gals with this being pregnant complication. Some exploration shows that using oral L-arginine could assist prevent preeclampsia in expecting gals.
  • Erectile dysfunction. Taking oral L-arginine could enhance sexual operate in men with erectile dysfunction owing to a physical trigger.
  • Peripheral arterial condition (PAD). When taken orally or by infusion for a shorter period of time of time, L-arginine may well enhance indications and blood stream in people today with this circulatory problem.

Our choose

Green light: Generally safe

Generally safe

L-arginine is regarded as to be typically safe. It could be effective at decreasing blood pressure, decreasing the indications of angina and PAD, and managing erectile dysfunction owing to a physical trigger.

Even so, if you choose a blood pressure drug, communicate to your medical doctor just before employing L-arginine.

Safety and facet results

Employing L-arginine orally or topically is typically regarded as safe.

Oral use of L-arginine could trigger:

  • Nausea, abdominal pain and diarrhea
  • Bloating
  • Gout
  • Headache
  • Allergic response
  • Airway swelling or worsening of bronchial asthma indications

L-arginine isn’t advised for people today who have had a current coronary heart assault owing to fears that the dietary supplement could improve the risk of loss of life.

L-arginine can worsen allergic reactions or bronchial asthma. Use the dietary supplement with caution if you have these ailments.

Be mindful about using L-arginine if you’ve got had cold sores or genital herpes. Much too significantly L-arginine in your method can perhaps set off the virus that causes those people ailments.

Interactions

Feasible interactions include:

  • Anticoagulants and anti-platelet prescription drugs, herbs and dietary supplements. These styles of prescription drugs, herbs and dietary supplements lower blood clotting. Taking L-arginine with them could improve the risk of bleeding.
  • Blood pressure prescription drugs, herbs and dietary supplements. L-arginine could decrease blood pressure in people today who have significant blood pressure. Combining use of L-arginine with a blood pressure drug, herb or dietary supplement could improve the risk of blood pressure getting to be too very low.
  • Diabetic issues prescription drugs, herbs and dietary supplements. L-arginine could decrease blood sugar ranges in people today with diabetic issues. If you happen to be using diabetic issues prescription drugs, herbs or dietary supplements, your dosage could will need to be adjusted.
  • Isoproterenol (Isuprel). Use of this coronary heart medication with L-arginine could trigger your blood pressure to develop into too very low.
  • Nitrates. Use of this upper body pain medication with L-arginine could trigger your blood pressure to develop into too very low.
  • Water supplements (potassium-sparing diuretics). You should not choose L-arginine with amiloride (Midamor), spironolactone (Aldactone, Carospir) or triamterene (Dyrenium). These medications can improve potassium ranges, growing the risk of developing a higher than usual level of potassium in your blood (hyperkalemia).
  • Sildenafil (Revatio, Viagra). Use of this erectile dysfunction medication with L-arginine could trigger your blood pressure to develop into too very low.

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