Women More Prone to Concussion’s Long-Term Harms

By Amy Norton
HealthDay Reporter

THURSDAY, April 8, 2021 (HealthDay Information) — After a concussion, ladies may perhaps be at heightened risk of long lasting bodily and mental signs and symptoms, a new analyze finds.

The analyze of 2,000 concussion victims located that ladies were more very likely than men to still have some signs and symptoms 1 year afterwards. The challenges included fuzzy memory and trouble concentrating, as very well as problems, dizziness or exhaustion.

In distinction, ladies and men confirmed comparable recovery situations right after traumatic injuries to other parts of the overall body.

The motives are unclear, but the analyze is not the initial to obtain sexual intercourse dissimilarities in concussion recovery. Lots of have located that on regular, ladies boost more slowly put up-concussion, irrespective of what brought on the harm.

But the new analyze also included a “handle” team of folks who experienced suffered orthopedic injuries, to see regardless of whether ladies tended to get better more slowly from injuries in standard.

And that was not the scenario.

It truly is an crucial obtaining, in accordance to Martina Anto-Ocrah, an assistant professor of emergency medication and neurology at the University of Rochester Medical Center.


She said it strengthens the scenario that women’s slower recovery is linked to concussion, precisely.

Anto-Ocrah co-wrote an editorial released with the analyze April 6 in the journal JAMA Community Open.

Though the findings may well sound dire, most ladies rebound quite rapidly right after a concussion.

“We be expecting most people to get better in weeks,” Anto-Ocrah said, noting that about 90% are back again on keep track of in 3 months.

But some folks have persistent bodily, mental or emotional signs and symptoms, for motives that are not absolutely apparent.

In this analyze, ladies did have greater prices of despair and stress and anxiety diagnoses ahead of the concussion, as opposed to men. And people are risk things for prolonged concussion signs and symptoms, Anto-Ocrah noted.

Even so, the researchers accounted for despair and stress and anxiety, and people diagnoses did not appear to be to clarify women’s more persistent signs and symptoms.

Irrespective of the cause, the findings provide validation. Some ladies, Anto-Ocrah noted, experience skepticism when they tell their physician they are still having concussion signs and symptoms many months right after the harm.


“This is supplemental proof that it’s not all in your head,” she said.

There’s no repair for the brain harm. But there are strategies to take care of signs and symptoms, Anto-Ocrah said. That could necessarily mean cognitive remedy for memory or pondering concerns, or treatment for challenges like persistent problems.

If ladies sense their lingering signs and symptoms are being dismissed, she urged them to “be persistent” in acquiring the care they have to have.

“You could exhibit your provider this analyze,” Anto-Ocrah advised.

The findings are primarily based on 2,000 concussion people and 299 with orthopedic injuries who were taken care of at any of eighteen U.S. hospitals.

Around 1 year, they periodically accomplished common questionnaires on bodily, mental and emotional signs and symptoms, as indicators of put up-traumatic anxiety dysfunction (PTSD).

On regular, feminine concussion people scored greater than their male counterparts on the measures of bodily and mental purpose (which means they experienced even worse signs and symptoms). The gender gap narrowed about time, as most people improved — but was still present 1 year afterwards.


The analyze are not able to reply the problem of why, said lead researcher Harvey Levin, a professor of bodily medication and rehabilitation at Baylor Higher education of Drugs in Houston.

It truly is possible, he said, that chronic swelling in the brain tissue or hormonal influences perform some part.

The brain has receptors for estrogen, and some research has hinted that ladies who maintain a concussion at specified situations in the menstrual cycle tend to have a slower recovery.

In this analyze, ladies concerning the ages of 35 and forty nine ordinarily experienced even worse signs and symptoms than both young and more mature ladies.

Anto-Ocrah termed the obtaining “interesting,” though there is no stable rationalization.

It truly is possible, she speculated, that it indicators a hormonal influence, because ladies in that age vary are nearing menopause.

Potential studies, Anto-Ocrah said, need to try to dig deeper by undertaking a “hormonal evaluation” of feminine concussion people — these types of as regardless of whether they were applying hormonal birth handle, experienced attained menopause, or were on menopausal hormone remedy.

For now, Levin said the findings on age need to be viewed with “warning,” and have to have confirmation in additional studies.


More data

The U.S. Centers for Disorder Manage and Prevention has more on concussion recovery.

Sources: Harvey Levin, PhD, professor, bodily medication and rehabilitation, Baylor Higher education of Drugs, Houston Martina Anto-Ocrah, PhD, MPH, assistant professor, emergency medication, neurology, and obstetrics and gynecology, University of Rochester Medical Center, Rochester, N.Y. JAMA Community Open, April 6, 2021, online